Intra-tumor Heterogeneity in Localized Lung Adenocarcinomas Delineated by Multi-region Sequencing

Cancers are composed of populations of cells with distinct molecular and phenotypic features, a phenomenon termed intra-tumor heterogeneity (ITH). ITH in lung cancers has not been well studied. We applied multi-region whole exome sequencing (WES) on 11 localized lung adenocarcinomas. All tumors show...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Science
Autori principali: Zhang, Jianjun, Fujimoto, Junya, Zhang, Jianhua, Wedge, David C., Song, Xingzhi, Zhang, Jiexin, Seth, Sahil, Chow, Chi-Wan, Cao, Yu, Gumbs, Curtis, Gold, Kathryn A., Kalhor, Neda, Little, Latasha, Mahadeshwar, Harshad, Moran, Cesar, Protopopov, Alexei, Sun, Huandong, Tang, Jiabin, Wu, Xifeng, Ye, Yuanqing, William, William N., Lee, Jack J., Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Futreal, P. Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354858/
https://ncbi.nlm.nih.gov/pubmed/25301631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256930
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi