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Dysfunctional HCN ion channels in neurological diseases

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed as four different isoforms (HCN1-4) in the heart and in the central and peripheral nervous systems. HCN channels are activated by membrane hyperpolarization at voltages close to resting membrane potentials and carry the...

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Pubblicato in:Front Cell Neurosci
Autori principali: DiFrancesco, Jacopo C., DiFrancesco, Dario
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354400/
https://ncbi.nlm.nih.gov/pubmed/25805968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00071
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