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Dysfunctional HCN ion channels in neurological diseases

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed as four different isoforms (HCN1-4) in the heart and in the central and peripheral nervous systems. HCN channels are activated by membrane hyperpolarization at voltages close to resting membrane potentials and carry the...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: DiFrancesco, Jacopo C., DiFrancesco, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354400/
https://ncbi.nlm.nih.gov/pubmed/25805968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00071
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