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A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects
PURPOSE: Valsartan, an angiotensin-receptor blocker, and rosuvastatin, a competitive inhibitor of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are frequently coadministered to treat patients with hypertension and dyslipidemia. The study reported here sought to evaluate the pharmacokinetic an...
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Published in: | Drug Des Devel Ther |
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Main Authors: | , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Dove Medical Press
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354399/ https://ncbi.nlm.nih.gov/pubmed/25767372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S76942 |
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