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A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects

PURPOSE: Valsartan, an angiotensin-receptor blocker, and rosuvastatin, a competitive inhibitor of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are frequently coadministered to treat patients with hypertension and dyslipidemia. The study reported here sought to evaluate the pharmacokinetic an...

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Publicat a:Drug Des Devel Ther
Autors principals: Jung, Jin Ah, Lee, Soo-Yun, Kim, Jung-Ryul, Ko, Jae-Wook, Jang, Seong Bok, Nam, Su Youn, Huh, Wooseong
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354399/
https://ncbi.nlm.nih.gov/pubmed/25767372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S76942
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