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Comparison of the Pharmacokinetic–Pharmacodynamic Relationships of Two Darbepoetin Alfa Formulations in Healthy Male Volunteers

OBJECTIVE: This study compared the pharmacokinetic (PK), pharmacodynamic (PD), and safety properties of the test (CJ-40001) and reference (NESP(®)) versions of darbepoetin alfa following a single subcutaneous (SC) or intravenous (IV) administration in healthy male subjects. METHODS: A single-blind,...

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Publicat a:BioDrugs
Autors principals: Kim, Seokuee, Hong, Taegon, Ko, Jae-Wook, Huh, Wooseong, Kim, Jung-Ryul
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373390/
https://ncbi.nlm.nih.gov/pubmed/30506495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-018-0323-0
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