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Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjects

BACKGROUND: Statins are effective agents in the primary and secondary prevention of cardiovascular disease, but treatment response to statins varies among individuals. We analyzed multiple genetic polymorphisms and assessed pharmacokinetic and lipid-lowering responses after atorvastatin 80 mg treatm...

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Publicado en:Drug Des Devel Ther
Autores principales: Woo, Hye In, Kim, Suk Ran, Huh, Wooseong, Ko, Jae-Wook, Lee, Soo-Youn
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391214/
https://ncbi.nlm.nih.gov/pubmed/28435225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S131487
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