PREFERENCE FOR DISTINCT FUNCTIONAL CONFORMATIONS OF THE DOPAMINE TRANSPORTER ALTERS THE RELATIONSHIP BETWEEN SUBJECTIVE EFFECTS OF COCAINE AND STIMULATION OF MESOLIMBIC DOPAMINE

BACKGROUND: Subjective effects related to cocaine abuse are primarily mediated by blockade of the dopamine (DA) transporter (DAT). The present study assessed the hypothesis that different conformational equilibria of the DAT regulate differences in extracellular DA induced by structurally diverse DA...

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Publicado en:Biol Psychiatry
Autores principales: Kohut, Stephen J., Hiranita, Takato, Hong, Soo-Kyung, Ebbs, Aaron L., Tronci, Valeria, Green, Jennifer, Garcés-Ramírez, Linda, Chun, Lauren E., Mereu, Maddalena, Newman, Amy H., Katz, Jonathan L., Tanda, Gianluigi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353924/
https://ncbi.nlm.nih.gov/pubmed/24853388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.03.031
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