Sigma receptor agonists: Receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis

BACKGROUND: Two subtypes of sigma (σ) receptors, σ(1) and σ(2), can be pharmacologically distinguished, and each may be involved in substance-abuse disorders. σ-receptor antagonists block cocaine place conditioning and σ-receptor agonists are self-administered in rats that previously self-administer...

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Detalhes bibliográficos
Main Authors: Garcés-Ramírez, Linda, Green, Jennifer L., Hiranita, Takato, Kopajtic, Theresa A., Mereu, Maddalena, Thomas, Alexandra, Mesangeau, Christophe, Narayanan, Sanju, McCurdy, Christopher R., Katz, Jonathan L., Tanda, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015019/
https://ncbi.nlm.nih.gov/pubmed/20950794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.07.026
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