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Activation Induced Deaminase in Antibody Diversification and Chromosome Translocation
DNA damage, rearrangement and mutation of the human genome are the basis of carcinogenesis and thought to be avoided at all costs. An exception is the adaptive immune system where lymphocytes utilize programmed DNA damage to effect antigen receptor diversification. Both B and T lymphocytes diversify...
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| Publicado no: | Adv Cancer Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353630/ https://ncbi.nlm.nih.gov/pubmed/22429855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394280-7.00005-1 |
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