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Reporter-based Growth Assay for Systematic Analysis of Protein Degradation

Protein degradation by the ubiquitin-proteasome system (UPS) is a major regulatory mechanism for protein homeostasis in all eukaryotes. The standard approach to determining intracellular protein degradation relies on biochemical assays for following the kinetics of protein decline. Such methods are...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Cohen, Itamar, Geffen, Yifat, Ravid, Guy, Ravid, Tommer
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353405/
https://ncbi.nlm.nih.gov/pubmed/25406949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52021
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