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The structural basis for specificity in lipoxygenase catalysis

Many intriguing facets of lipoxygenase (LOX) catalysis are open to a detailed structural analysis. Polyunsaturated fatty acids with two to six double bonds are oxygenated precisely on a particular carbon, typically forming a single chiral fatty acid hydroperoxide product. Molecular oxygen is not bou...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Newcomer, Marcia E, Brash, Alan R
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353356/
https://ncbi.nlm.nih.gov/pubmed/25524168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2626
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