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Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling
Increasing bacterial resistance to available antibiotics makes the discovery of novel efficacious antibacterial agents a priority. A previous report showed that listeriolysin O (LLO) is a critical virulence factor and suggested that it is a target for developing anti-virulence drugs against Listeria...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352855/ https://ncbi.nlm.nih.gov/pubmed/25749652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08864 |
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