Phloretin Attenuates Listeria monocytogenes Virulence Both In vitro and In vivo by Simultaneously Targeting Listeriolysin O and Sortase A

The critical roles of sortase A (SrtA) and listeriolysin O (LLO) in Listeria monocytogenes pathogenicity render these two virulence factors as ideal targets for the development of anti-virulence agents against L. monocytogenes infection. Additionally, the structures of SrtA and LLO are highly conser...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wang, Jianfeng, Liu, Bowen, Teng, Zihao, Zhou, Xuan, Wang, Xiyan, Zhang, Bing, Lu, Gejin, Niu, Xiaodi, Yang, Yongjun, Deng, Xuming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244253/
https://ncbi.nlm.nih.gov/pubmed/28154809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00009
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