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A Dual-Reporter System for Real-Time Monitoring and High-throughput CRISPR/Cas9 Library Screening of the Hepatitis C Virus

The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas and infects approximately 170 million people worldwide. Although several reporter systems have been developed, many shortcomings limit their use in the assessment of HCV infec...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ren, Qingpeng, Li, Chan, Yuan, Pengfei, Cai, Changzu, Zhang, Linqi, Luo, Guangxiang George, Wei, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352851/
https://ncbi.nlm.nih.gov/pubmed/25746010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08865
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