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Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease
Subunit vaccines comprised of glycoprotein D (gD-2) failed to prevent HSV-2 highlighting need for novel strategies. To test the hypothesis that deletion of gD-2 unmasks protective antigens, we evaluated the efficacy and safety of an HSV-2 virus deleted in gD-2 and complemented allowing a single roun...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352706/ https://ncbi.nlm.nih.gov/pubmed/25756612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06054 |
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