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Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry

Herpes simplex virus (HSV) entry is associated with Akt translocation to the outer leaflet of the plasma membrane to promote a complex signaling cascade. We hypothesized that phospholipid scramblase-1 (PLSCR1), a calcium responsive enzyme that flips phosphatidylserines between membrane leaflets, mig...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Cheshenko, Natalia, Pierce, Carl, Herold, Betsy C.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766253/
https://ncbi.nlm.nih.gov/pubmed/29293671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006766
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