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Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry

Herpes simplex virus (HSV) entry is associated with Akt translocation to the outer leaflet of the plasma membrane to promote a complex signaling cascade. We hypothesized that phospholipid scramblase-1 (PLSCR1), a calcium responsive enzyme that flips phosphatidylserines between membrane leaflets, mig...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Cheshenko, Natalia, Pierce, Carl, Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766253/
https://ncbi.nlm.nih.gov/pubmed/29293671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006766
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