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Role of αA-crystallin-derived αA66-80 peptide in guinea pig lens crystallin aggregation and insolubilization

Earlier we reported that low molecular weight (LMW) peptides accumulate in aging human lens tissue and that among the LMW peptides, the chaperone inhibitor peptide αA66-80, derived from α-crystallin protein, is one of the predominant peptides. We showed that in vitro αA66-80 induces protein aggregat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Eye Res
Päätekijät: Raju, Murugesan, Mooney, Brian P., Thakkar, Kavi M., Giblin, Frank J., Schey, Kevin L., Sharma, K. Krishna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352376/
https://ncbi.nlm.nih.gov/pubmed/25639202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.01.024
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