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αA-Crystallin Peptide (66) SDRDKFVIFLDVKHF (80) Accumulating in Aging Lens Impairs the Function of α-Crystallin and Induces Lens Protein Aggregation

BACKGROUND: The eye lens is composed of fiber cells that are filled with α-, β- and γ-crystallins. The primary function of crystallins is to maintain the clarity of the lens through ordered interactions as well as through the chaperone-like function of α-crystallin. With aging, the chaperone functio...

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Hlavní autoři: Santhoshkumar, Puttur, Raju, Murugesan, Sharma, K. Krishna
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084282/
https://ncbi.nlm.nih.gov/pubmed/21552534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019291
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