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Role of αA-crystallin-derived αA66-80 peptide in guinea pig lens crystallin aggregation and insolubilization
Earlier we reported that low molecular weight (LMW) peptides accumulate in aging human lens tissue and that among the LMW peptides, the chaperone inhibitor peptide αA66-80, derived from α-crystallin protein, is one of the predominant peptides. We showed that in vitro αA66-80 induces protein aggregat...
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| Publié dans: | Exp Eye Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352376/ https://ncbi.nlm.nih.gov/pubmed/25639202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.01.024 |
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