Functional interplay between MDM2, p63/p73 and mutant p53

Many cancers express mutant p53 proteins that have lost wild-type tumor suppressor activity and, in many cases, have acquired oncogenic functions that can contribute to tumor progression. These activities of mutant p53 reflect interactions with several other proteins, including the p53 family member...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Stindt, M H, Muller, P A J, Ludwig, R L, Kehrloesser, S, Dötsch, V, Vousden, K H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351904/
https://ncbi.nlm.nih.gov/pubmed/25417702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.359
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