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Independent recruitment of Igh alleles in V(D)J recombination
How the vast majority of B cells express only one of the two alleles at their immunoglobulin loci remains a biological puzzle. Here, in mice reconstituted with a single haematopoietic stem cell, we demonstrate that each of the two immunoglobulin heavy chain (Igh) alleles has a similar probability to...
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| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Pub. Group
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351640/ https://ncbi.nlm.nih.gov/pubmed/25517887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6623 |
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