Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity

Predicting clinical response to anticancer drugs remains a major challenge in cancer treatment. Emerging reports indicate that the tumour microenvironment and heterogeneity can limit the predictive power of current biomarker-guided strategies for chemotherapy. Here we report the engineering of perso...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Majumder, Biswanath, Baraneedharan, Ulaganathan, Thiyagarajan, Saravanan, Radhakrishnan, Padhma, Narasimhan, Harikrishna, Dhandapani, Muthu, Brijwani, Nilesh, Pinto, Dency D., Prasath, Arun, Shanthappa, Basavaraja U., Thayakumar, Allen, Surendran, Rajagopalan, Babu, Govind K., Shenoy, Ashok M., Kuriakose, Moni A., Bergthold, Guillaume, Horowitz, Peleg, Loda, Massimo, Beroukhim, Rameen, Agarwal, Shivani, Sengupta, Shiladitya, Sundaram, Mallikarjun, Majumder, Pradip K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351621/
https://ncbi.nlm.nih.gov/pubmed/25721094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7169
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