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EXTH-42. CANSCRIPT MAY PREDICT A SUBSET OF GLIOBLASTOMAS THAT RESPOND TO SP1 BLOCKERS
INTRODUCTION: Perturbation of SP1 has long been implicated in the pathogenesis and drug resistance in Glioblastomas. Multiple mechanisms including upregulation of BACH 1 by antagonizing the function of P53 and hypomethylating MGMT have been described. In addition, the increased expression of genes i...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217336/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.390 |
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