EXTH-42. CANSCRIPT MAY PREDICT A SUBSET OF GLIOBLASTOMAS THAT RESPOND TO SP1 BLOCKERS

INTRODUCTION: Perturbation of SP1 has long been implicated in the pathogenesis and drug resistance in Glioblastomas. Multiple mechanisms including upregulation of BACH 1 by antagonizing the function of P53 and hypomethylating MGMT have been described. In addition, the increased expression of genes i...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Ray, Amitava, Thiyagarajan, Sarvanan, Majumdar, Biswanath, Radhakrishnan, Padhma, Kamath, Ajith, Kumar, Dilli, Majumdar, Pradip
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217336/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.390
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