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Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

Protein disulfide isomerase (PDI), secreted from platelets and endothelial cells after injury, is required for thrombus formation. The effect of platelet and endothelial cell granule contents on PDI-mediated thrombus formation was studied by intravital microscopy using a mouse model of Hermansky-Pud...

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Vydáno v:Blood
Hlavní autoři: Sharda, Anish, Kim, Sarah H., Jasuja, Reema, Gopal, Srila, Flaumenhaft, Robert, Furie, Barbara C., Furie, Bruce
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351508/
https://ncbi.nlm.nih.gov/pubmed/25593336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-597419
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