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Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism
The difficulty in maintaining the reconstituting capabilities of hematopoietic stem cells (HSCs) in culture outside of the bone marrow microenvironment has severely limited their utilization for clinical therapy. This hurdle is largely due to the differentiation of long-term stem cells. Emerging evi...
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| Publié dans: | Blood |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351504/ https://ncbi.nlm.nih.gov/pubmed/25593337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568949 |
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