Decellularized Wharton jelly matrix: a biomimetic scaffold for ex vivo hematopoietic stem cell culture

Hematopoietic stem progenitor cells (HSPCs) reside in the bone marrow (BM) hematopoietic “niche,” a special 3-dimensional (3D) microenvironment that regulates HSPC self-renewal and multipotency. In this study, we evaluated a novel 3D in vitro culture system that uses components of the BM hematopoiet...

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Vydáno v:Blood Adv
Hlavní autoři: Li, Dandan, Chiu, Grace, Lipe, Brea, Hopkins, Richard A., Lillis, Jacquelyn, Ashton, John M., Paul, Soumen, Aljitawi, Omar S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457237/
https://ncbi.nlm.nih.gov/pubmed/30940636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019315
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