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Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism

The difficulty in maintaining the reconstituting capabilities of hematopoietic stem cells (HSCs) in culture outside of the bone marrow microenvironment has severely limited their utilization for clinical therapy. This hurdle is largely due to the differentiation of long-term stem cells. Emerging evi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Liu, Xia, Zheng, Hong, Yu, Wen-Mei, Cooper, Todd M., Bunting, Kevin D., Qu, Cheng-Kui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351504/
https://ncbi.nlm.nih.gov/pubmed/25593337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568949
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