Dexmedetomidine inhibits Tetrodotoxin-resistant Na(v)1.8 sodium channel activity through G(i/o)-dependent pathway in rat dorsal root ganglion neurons

BACKGROUND: Systemically administered dexmedetomidine (DEX), a selective α2 adrenergic receptor (α2-AR) agonists, produces analgesia and sedation. Peripherally restricted α2-AR antagonist could block the analgesic effect of systemic DEX on neuropathic pain, with no effect on sedation, indicating per...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Gu, Xi-Yao, Liu, Ben-Long, Zang, Kai-Kai, Yang, Liu, Xu, Hua, Pan, Hai-Li, Zhao, Zhi-Qi, Zhang, Yu-Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350947/
https://ncbi.nlm.nih.gov/pubmed/25761941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0105-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados