Effects of (−)-Gallocatechin-3-Gallate on Tetrodotoxin-Resistant Voltage-Gated Sodium Channels in Rat Dorsal Root Ganglion Neurons

The (−)-gallocatechin-3-gallate (GCG) concentration in some tea beverages can account for as much as 50% of the total catechins. It has been shown that catechins have analgesic properties. Voltage-gated sodium channels (Nav) mediate neuronal action potentials. Tetrodotoxin inhibits all Nav isoforms,...

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Detalhes bibliográficos
Main Authors: Jian-Min Jiang, Pei-Qing Liu, Jin-Lei Guo, Yan-Yan Jia, Yan Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2013-05-01
Colecção:International Journal of Molecular Sciences
Assuntos:
catechins
(−)-gallocatechin-3-gallate
Na+ channel
dorsal root ganglion
tetrodotoxin-resistant
Acesso em linha:http://www.mdpi.com/1422-0067/14/5/9779
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