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Low concentrations of tetrodotoxin interact with tetrodotoxin-resistant voltage-gated sodium channels
BACKGROUND AND PURPOSE: Tetrodotoxin (TTX) is used to distinguish between two classes of voltage-gated sodium channel (VGSC)—TTX sensitive (TTXS) and TTX resistant (TTXR). The resistance of TTXR VGSCs is thought to result from a low binding affinity of TTX, although at high TTX concentrations channe...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527855/ https://ncbi.nlm.nih.gov/pubmed/18552876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.235 |
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