Up-regulation of Tetrodotoxin-Sensitive Sodium Currents by Prostaglandin E(2) in Type-4 Rat Dorsal Root Ganglion Cells

Mechanisms were studied by which prostaglandin E(2) (PGE(2)) up-regulates Na(+) currents (I(Na)) in medium diameter dorsal root ganglion (DRG) cells that express large T-type Ca(2+) currents (type-4 DRG cells). PGE(2) or the adenylyl cyclase (AC) activator forskolin (10 µM) up-regulated peak I(Na) e...

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Detalhes bibliográficos
Main Authors: Tripathi, Pradeep K., Cardenas, Carla G., Cardenas, Carlos A., Scroggs, Reese S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112009/
https://ncbi.nlm.nih.gov/pubmed/21530616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.04.015
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