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Role of p38 mitogen-activated protein kinase in vascular endothelial aging: Interaction with Arginase-II and S6K1 signaling pathway

p38 mitogen-activated protein kinase (p38) regulates cellular senescence and senescence-associated secretory phenotype (SASP), i.e., secretion of cytokines and/or chemokines. Previous work showed that augmented arginase-II (Arg-II) and S6K1 interact with each other to promote endothelial senescence...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wu, Zongsong, Yu, Yi, Liu, Chang, Xiong, Yuyan, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350325/
https://ncbi.nlm.nih.gov/pubmed/25635535
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