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Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling

BACKGROUND: Augmented arginase-II (Arg-II) is implicated in endothelial senescence and inflammation through a mutual positive regulatory circuit with S6K1. This study was conducted to investigate whether Arg-I, another isoform of arginase that has been also reported to play a role in vascular endoth...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Res Notes
Hauptverfasser: Zhu, Cuicui, Yu, Yi, Montani, Jean-Pierre, Ming, Xiu-Fen, Yang, Zhihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290613/
https://ncbi.nlm.nih.gov/pubmed/28153047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2399-x
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