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Arginase-II Deficiency Extends Lifespan in Mice
The mitochondrial arginase type II (Arg-II) has been shown to interact with ribosomal protein S6 kinase 1 (S6K1) and mitochondrial p66(Shc) and to promote cell senescence, apoptosis and inflammation under pathological conditions. However, the impact of Arg-II on organismal lifespan is not known. In...
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| Udgivet i: | Front Physiol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596098/ https://ncbi.nlm.nih.gov/pubmed/28943853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00682 |
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