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Long term exposure to L-arginine accelerates endothelial cell senescence through arginase-II and S6K1 signaling

L-arginine supplementation is proposed to improve health status or as adjunct therapy for diseases including cardiovascular diseases. However, controversial results and even detrimental effects of L-arginine supplementation are reported. We investigate potential mechanisms of L-arginine-induced detr...

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Detalhes bibliográficos
Main Authors: Xiong, Yuyani, Fru, Michael Forbiteh, Yu, Yi, Montani, Jean-Pierre, Ming, Xiu-Fen, Yang, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069264/
https://ncbi.nlm.nih.gov/pubmed/24860943
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