Endogenous Interferon-β-Inducible Gene Expression and Interferon-β-Treatment Are Associated with Reduced T Cell Responses to Myelin Basic Protein in Multiple Sclerosis

Autoreactive CD4(+) T-cells are considered to play a major role in the pathogenesis of multiple sclerosis. In experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, exogenous and endogenous type I interferons restrict disease severity. Recombinant interferon-β is used for...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Börnsen, Lars, Romme Christensen, Jeppe, Ratzer, Rikke, Hedegaard, Chris, Søndergaard, Helle B., Krakauer, Martin, Hesse, Dan, Nielsen, Claus H., Sorensen, Per S., Sellebjerg, Finn
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349448/
https://ncbi.nlm.nih.gov/pubmed/25738751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118830
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker