Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

Pathology studies of progressive multiple sclerosis (MS) indicate a major role of inflammation including Th17-cells and meningeal inflammation with ectopic lymphoid follicles, B-cells and plasma cells, the latter indicating a possible role of the newly identified subset of follicular T-helper (T(FH)...

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Autores principales: Christensen, Jeppe Romme, Börnsen, Lars, Ratzer, Rikke, Piehl, Fredrik, Khademi, Mohsen, Olsson, Tomas, Sørensen, Per Soelberg, Sellebjerg, Finn
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585852/
https://ncbi.nlm.nih.gov/pubmed/23469245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057820
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