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Comparison of T7E1 and Surveyor Mismatch Cleavage Assays to Detect Mutations Triggered by Engineered Nucleases
Genome editing using engineered nucleases is used for targeted mutagenesis. But because genome editing does not target all loci with similar efficiencies, the mutation hit-rate at a given locus needs to be evaluated. The analysis of mutants obtained using engineered nucleases requires specific metho...
में बचाया:
| में प्रकाशित: | G3 (Bethesda) |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Genetics Society of America
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4349094/ https://ncbi.nlm.nih.gov/pubmed/25566793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.015834 |
| टैग : |
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