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A Simple Method To Detect Point Mutations in Aspergillus fumigatus cyp51A Gene Using a Surveyor Nuclease Assay

One of the main mechanisms of azole resistance of Aspergillus fumigatus is thought to be a reduction in the drug’s affinity for the target molecule, Cyp51A, due to its amino acid mutation(s). It is known that the azole resistance pattern is closely related to the mutation site(s) of the molecule. In...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Arai, Teppei, Majima, Hidetaka, Watanabe, Akira, Kamei, Katsuhiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179262/
https://ncbi.nlm.nih.gov/pubmed/32015034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02271-19
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