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Screening for Mutations in Kidney-Related Genes Using SURVEYOR Nuclease for Cleavage at Heteroduplex Mismatches

SURVEYOR is a new mismatch-specific plant DNA endonuclease that is very efficient for mutation scanning in heteroduplex DNA. It is much faster, cheaper, more sensitive, and easier to perform than other “traditional” mutation detection methods such as single-strand conformation polymorphism analysis,...

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Main Authors: Voskarides, Konstantinos, Deltas, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710707/
https://ncbi.nlm.nih.gov/pubmed/19525337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.080144
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