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Screening for Mutations in Kidney-Related Genes Using SURVEYOR Nuclease for Cleavage at Heteroduplex Mismatches

SURVEYOR is a new mismatch-specific plant DNA endonuclease that is very efficient for mutation scanning in heteroduplex DNA. It is much faster, cheaper, more sensitive, and easier to perform than other “traditional” mutation detection methods such as single-strand conformation polymorphism analysis,...

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Main Authors: Voskarides, Konstantinos, Deltas, Constantinos
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710707/
https://ncbi.nlm.nih.gov/pubmed/19525337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.080144
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