Porphyromonas gingivalis Gingipains Selectively Reduce CD14 Expression, Leading to Macrophage Hyporesponsiveness to Bacterial Infection

Cysteine proteases (gingipains) from Porphyromonas gingivalis are key virulence factors in chronic periodontitis. Innate immune receptors CD14, Toll-like receptor (TLR) 2 and TLR4 are important in P. gingivalis recognition. We examined the ability of gingipains to cleave CD14, TLR2 and TLR4, and the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Innate Immun
Egile Nagusiak: Wilensky, Asaf, Tzach-Nahman, Rinat, Potempa, Jan, Shapira, Lior, Nussbaum, Gabriel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: S. Karger AG 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348206/
https://ncbi.nlm.nih.gov/pubmed/25228314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365970
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak