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Axonal and Schwann Cell BACE1 Is Equally Required for Remyelination of Peripheral Nerves
Inhibition of β-site APP cleaving enzyme 1 (BACE1) is being pursued as a therapeutic target for treating patients with Alzheimer's disease because BACE1 is the sole β-secretase for generating β-amyloid peptide. Knowledge regarding the other cellular functions of BACE1 is therefore critical for...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348183/ https://ncbi.nlm.nih.gov/pubmed/25740511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5207-14.2015 |
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