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Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves
BACE1 is a promising therapeutic and preventive target for Alzheimer’s disease because it is essential for amyloid deposition. However, the recent demonstration of BACE1 in modulating developmental myelination in both peripheral and central nervous systems raises a concern of its effect on myelin ma...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Federation of American Societies for Experimental Biology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493455/ https://ncbi.nlm.nih.gov/pubmed/18413858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-106666 |
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