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BACE1 regulates the proliferation and cellular functions of Schwann cells
BACE1 is an indispensable enzyme for generating β-amyloid peptides, which are excessively accumulated in brains of Alzheimer’s patients. However, BACE1 is also required for proper myelination of peripheral nerves, as BACE1-null mice display hypomyelination. In order to determine the precise effects...
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| Publicado no: | Glia |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357169/ https://ncbi.nlm.nih.gov/pubmed/28191691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23122 |
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