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Effects of short-term endurance exercise training on acute doxorubicin-induced FoxO transcription in cardiac and skeletal muscle

Doxorubicin (DOX) is a potent antitumor agent used in cancer treatment. Unfortunately, DOX can induce myopathy in both cardiac and skeletal muscle, which limits its clinical use. Importantly, exercise training has been shown to protect against DOX-mediated cardiac and skeletal muscle myopathy. Howev...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Kavazis, Andreas N., Smuder, Ashley J., Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347740/
https://ncbi.nlm.nih.gov/pubmed/24947024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00210.2014
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