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Exercise protects against doxorubicin-induced oxidative stress and proteolysis in skeletal muscle

Doxorubicin (Dox) is a potent antitumor agent used in cancer treatment. Unfortunately, Dox is myotoxic and results in significant reductions in skeletal muscle mass and function. Complete knowledge of the mechanism(s) by which Dox induces toxicity in skeletal muscle is incomplete, but it is establis...

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書目詳細資料
Main Authors: Smuder, Ashley J., Kavazis, Andreas N., Min, Kisuk, Powers, Scott K.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075128/
https://ncbi.nlm.nih.gov/pubmed/21310889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00677.2010
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