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Exercise protects against doxorubicin-induced oxidative stress and proteolysis in skeletal muscle

Doxorubicin (Dox) is a potent antitumor agent used in cancer treatment. Unfortunately, Dox is myotoxic and results in significant reductions in skeletal muscle mass and function. Complete knowledge of the mechanism(s) by which Dox induces toxicity in skeletal muscle is incomplete, but it is establis...

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Hlavní autoři: Smuder, Ashley J., Kavazis, Andreas N., Min, Kisuk, Powers, Scott K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075128/
https://ncbi.nlm.nih.gov/pubmed/21310889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00677.2010
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