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Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72

Doxorubicin (Dox) is an antitumor agent used in cancer treatment, but its clinical use is limited due to cardiotoxicity. Although exercise training can defend against Dox-mediated cardiac damage, the means for this cardioprotection remain unknown. To investigate the mechanism(s) responsible for exer...

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Main Authors: Kavazis, Andreas N., Smuder, Ashley J., Min, Kisuk, Tümer, Nihal, Powers, Scott K.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993189/
https://ncbi.nlm.nih.gov/pubmed/20833957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00585.2010
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